Introduction to immunology, antigen and antibody recognition and selection, cellular and humoral immunity, hypersensitivity reactions are the main topics. Vaccines, vaccine generation, importance and action mechanisms of vaccines are covered as well as transplantation of tissues and organs, methods and possible complications. Antibody development and antibody engineering, immune cell structure/function/sorting and molecular basics and techniques of immunology are covered. The structure of antibodies, T-cell and B-cell receptors, MHC, and their functions are included among topics. V(D)J recombination, it’s mechanisms and enzymes are discussed as well as the details of somatic hypermutation. Positive and negative selection of immune cells, potential complications and autoimmune diseases that can arise from immune system dysfunction are discussed.
- Teacher: Ender Volkan