Pharmacogenetics and Pharmacogenomics lecture
will be dealing with interaction of genetics and polymorphism on drug
pharmacokinetic and pharmacodynamics parameters. The aim of this course is to
deal with the basis of gene therapy, genetic variation in the effects of drugs
and xenobiotic substances on the body, and in the body’s reactions to drugs,
translational, and pharmaceutical research, and application of genomic
technologies to new drug discovery. Genetically engineering drugs and their
application in treatment of certain diseases such as cancer, diabetes, heart
problems, Alzheimer’s and other neurodegenerative diseases and atherosclerosis
will be also considered. While genetic variation is an important parameter on
drug interactions, the contributions of epigenetic and non-genetic factors to
drug disposition and drug response will be explained in this lecture.
- Teacher: Ovgu Isbilen