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This course is designed for students to gain an understanding of statistical data analyses and experimental design in the field of biological sciences, including statistical analyses used in epidemiology. Practical and non-theoretical approaches to the statistical analyses of laboratory data is discussed; including experimental design, mistakes in experimental design, rigor and reproducibility and bias in scientific research. Topics and statistical tests such as hypothesis testing, T-tests, 1-Way and Multi-Way ANOVAs, post-hoc tests, correlations and regressions, non-parametric statistics, power analyses and dose-response analyses are presented with examples from several fields with an emphasis on biotechnology. Prism from GraphPad is introduced and used throughout the course, as well as SPSS. Literature from biotechnology research will be used to provide students examples of statistical analyses of real-life data.
- Teacher: Zalihe Yarkiner
This course is designed to explore the scientific principles that govern human reproduction. There will be an anatomical overview of female and male reproductive systems. There will also be a focus on menstrual and ovarian cycles, fertilization, implantation and embryonic development; development from fertilization to the blastocyst stage, implantation and placental development and embryogenesis. Reproductive disorders and abnormalities such as ectopic pregnancies, miscarriages, preterm births, fetal disorders, placental complications, parturition, and lactation are discussed, including teratology. Special topics such as infertility and the environmental causes of infertility, current assisted reproductive technologies; their development, advancement, risks, controversies and the future outlook of such technologies will be discussed. Additionally, the pathophysiology of female and male reproductive systems, in vitro fertilization and fertility medications will be explained.
- Teacher: Munevver Serdarogullari
This course aims to introduce students to stem cell biology and research; the different types, characteristics and functions of stem cells (embryonic, adult, cord blood and amniotic and induced pluripotent stem cells), stem cell generation, regulation and differentiation in vitro and in vivo and how induced pluripotent stem cells are derived and used for research. Experimental systems to be studied include human stem cells as well as mouse, zebrafish, and Drosophila model systems. Furthermore, there will be an emphasis on how stem cells can be used to repair organ and tissue damage such as paralyses and burns. In addition, treatment of a vast array of diseases like diabetes, cancers, Parkinson's, dementia, neuropathies, congenital hearing loss, cystic fibrosis and cardiovascular diseases will be covered
- Teacher: Deran Erdengiz
This course is designed to examine the molecular and cellular mechanisms for a variety of diseases and pathologies affecting the structure and function of human tissues and organs, including the corresponding animal models which are used in research. The genetic, biochemical, inflammatory, immunological and neoplastic mechanisms of these diseases will be presented. Cancers, neurological, cardiovascular, metabolic, autoimmune, coagulation, deficiency, psychological and pathogenic disorders will be discussed. The epidemiology, genetics, environmental factors, symptoms, diagnoses, pathophysiology and treatments of these disorders will be examined in the context of biotechnological research, with heavy focus on current literature. Online research and clinical trial databases will be used in parallel, for students to gain an understanding of the most current developments and advancements in disease pathology, diagnostics and therapeutics.
- Teacher: Ender Volkan
The main purpose of this course is to teach students about the principles, concepts and applications of science and technology relevant to the development of food products and end-uses for food biotechnology. Applications of modern genetics as well as an enzyme, cell, tissue, and organ-based biological processes to produce and improve foods, food ingredients, and functional foods will be discussed. Furthermore, food waste remediation and management be covered. Fundamental theory of food biotechnology will be examined including traditional fermentation applications, fermentation for food ingredients, genetic engineering in the food industry, molecular feedings and biosensory technologies for the analyses of nutrients, contaminants and toxins. Additionally, food production legislations and the ethics of food biotechnology will be presented with discussion from current literature.